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by Source: Westport Newsroom
January 1, 1999
WESTPORT (Reuters) - The US Department of Veterans Affairs announced that it will lead a $20 million effort to conduct large-scale randomized studies on treatments for Gulf War veterans with symptoms of undiagnosed illnesses.
The Department of Veterans Affairs will conduct the studies with the US Department of Defense. Experts from the National Institutes of Health, the Department of Defense, and universities advised the Veterans Affairs Cooperative Studies Evaluation Committee in the design of the trial protocols.
Dr. John R. Feussner, VA chief research and development officer and chairperson of the Research Working Group of the Persian Gulf Veterans Coordinating Board, said in a press release, "Despite the lack of a comprehensive case definition for the symptom complex often called Gulf War veterans' illnesses, [the Department of Veterans Affairs] has identified subgroups of patients for whom potential treatments are now appropriate."
The studies consist of an Exercise/Behavioral Therapy Trial and an Antibiotic Treatment Trial.
The Exercise Behavioral Trial will involve close to 1,000 Gulf War veterans who experienced at least two of three unexplained symptoms of fatigue, muscle and joint pain, and memory and cognitive problems. Researchers will randomly assign veterans to receive either aerobic exercise training and cognitive behavioral therapy or customary medical care.
The Antibiotic Treatment Trial will involve hundreds of ill veterans who will be randomly assigned either to a placebo group or to a treatment group. The treatment arm will take oral doxycycline for 12 months. Volunteers for this study must show evidence of infection with Mycoplasma fermentans, a proposed infectious cause of symptoms reported by Gulf War veterans.
Both studies are being led by Dr. Sam Donta, an infectious disease specialist with the Boston VA Medical Center and a professor of medicine at Boston University. The Veterans Administration will recruit veterans for the studies after January 1, 1999.
-Westport Newsroom
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