Are Your Cells Stressed Out? Give Them the Nutrition They Need
Fatigue is one of the first outward signs of cellular deterioration. When a cell membrane deteriorates, it loses its fluidity, which is the ability to absorb critical nutrients into the cell for optimal health and energy production. Numerous factors exert damaging stress on your cells every day. Researchers have found that key lipids are able to improve and maintain the fluidity of cell membranes – resulting in effective absorption of nutrients, which leads to increased energy production.

Delivering intact phospholipids is a unique advanced nutritional technology that helps rejuvenate stressed out cells by transporting key vitamins, critical phospholipids, and essential fatty acids into cells, and particularly into cells’ mitochondria (my-tow-con-dree-ah). Mitochondria are the tiny ‘power plants’ within each cell that generate the energy you need to function and feel invigorated throughout the day. Phospholipids help nourish and strengthen cellular and mitochondrial membranes to promote enhanced nutrient absorption necessary for optimal energy production. This crucial cellular support revives your metabolism to produce more energy, more efficiently.

Fluid Cell Membranes Allow Nutrients In – And Help Ignite Mitochondrial Function

Protecting cell membrane integrity enhances cellular health, which promotes energy and efficient metabolism. A cell’s healthy functional capacity can be measured, in part, by the fluidity of its membranes and its cell-to-cell communication capacity. One of the most common forms of cell damage is created by free radicals, which reduce membrane fluidity and impair cell-to-cell function.

The main group of lipids that are vitally important to building cell strength are called polyunsaturated phosphatidyl-choline (PPC) molecules. PPC molecules help enhance the structure, function and renewal of all cellular and mitochondrial membranes. Healthy cellular and mitochondrial membranes enable better utilization of nutrients and improved mitochondrial function. The result? More energy.

NT Factor® Stops Fatigue in Multiple Studies!

Human Fatigue Study – 33% Fatigue Reduction in 8 Weeks

A scientific study(1) was conducted to determine whether fatigue, as defined by the reliable Piper Fatigue Scale (PFS), could be significantly relieved by use of a phosphoglycolipid-rich dietary supplement – NT Factor®, in a targeted sampling of the general population (mean age=50.3 years). Sixty four (64) subjects completed the self-reported PFS and were admitted to the study when their self reported sign/symptom severity scores were converted to fatigue scores and rated as high moderate to severe fatigue. The PFS has been shown to accurately reflect the multifactorial nature of fatigue through statistical factor analysis and clinical studies.

Results: Using the Piper Fatigue Scale (PFS), there was a 33% reduction in fatigue after eight weeks on NT Factor®. The PFS rates fatigue from a score of 0 (no fatigue) to 10 (severe fatigue). The average initial fatigue score for the group before treatment was reported as severe (mean score=7.9). After the fourth week of supplementation, the average fatigue score was rated as moderate (mean=6.1). At the eighth week of supplementation, the final average score was rated as moderate (mean=4.7). In this self-reported study, dietary supplementation significantly reduced fatigue as measured by the PFS.

Human Chemotherapy Study – 75% Experienced Improved Quality of Life

Fatigue is one of the most common complaints of chemotherapy patients, in addition to the numerous adverse reactions associated with the administration of chemotherapy. The effect of a supplement containing NT Factor® has been documented in a double-blind placebo-controlled crossover randomized study on patients undergoing chemotherapy.(2) Thirty-six patients were enrolled in the 12-week pilot study.

The consumption of the recommended daily dosage of the supplement with NT Factor® resulted in an improvement or no change or worsening in chemotherapy-related side effects of fatigue, nausea, impaired taste, diarrhea, general tiredness, constipation and insomnia. These results were assessed by standard Quality of Life (QOL) questionnaires completed by patients and nurses in the offices of oncologists participating in the study. Results: Nurses reported that for those patients who began on placebo and crossed over to the supplement with NT Factor®, 75% experienced an improvement in quality of life indicators and a decrease in chemotherapy-related side effects. For those patients who began on the supplement with NT Factor® and crossed over to placebo, nurses reported that 64% reported an improvement in quality of life indicators and a decrease in side effects.

The results of this pilot study indicate that patient perception of benefit with NT Factor® supplementation to chemotherapy is significant in reducing fatigue, vomiting, nausea and diarrhea.

Human Mitochondrial Study – Restored Cellular Function of 60 Year-Olds to Young Adult Levels

Decreased mitochondrial function is a characteristic of aging and fatigue. Researchers from the University of California at Irvine and The Institute for Molecular Medicine in Huntington Beach, CA(3) evaluated the effects of NT Factor® on mitochondrial function in 20 people (average age 60 years) to determine whether mitochondrial function is reduced in aging subjects with mild to moderately severe fatigue, and if the process could be reversed with NT Factor® supplementation in concert with improvement in fatigue scores.

Mitochondria of peripheral blood cells were isolated using flow cytometry and stained with fluorescent reducing dye Rhodamine-123. Results: Improvement of mitochondrial function in 8 weeks reached levels normally seen in young adults. Continued use maintained improved levels. Patients’ fatigue improvement as measured by the published Piper Fatigue Scale correlated with increased mitochondrial function. A washout period caused function to return to near baseline indicating a need for continued use. Dosing during the study was 3 tablets twice daily. All statistical measurements were considered significant.

Animal Mitochondrial Study – Improved Cell Function, Hearing, and Slowed Aging

Research conducted at the Henry Ford Health Systems Department of Otolaryngology-Head and Neck Surgery(4,5) investigated the effects of polyunsaturated phosphatidylcholine (PPC) in NT Factor® on age-related hearing loss in rats by evaluating its ability to preserve mitochondrial function, protect mitochondrial DNA from oxidative damage and preserve auditory sensitivity. The rat subjects were given a dose of 300mg/kg per day of NT Factor®. The animals were divided randomly into two groups (7 in each group). Group-1 served as the control, and group-2 as the experimental group. At the onset of the study, auditory brainstem responses were obtained to measure baseline hearing thresholds. Age-associated changes in hearing sensitivities were then recorded at two-month intervals for six months.

Results: There was a statistically significant protective effect of PPC on the experimental subjects and a continued decline in hearing in the control subjects. The results of this experiment suggest that NT Factor® containing PPC may protect mitochondrial function by preserving the age-related decline in mitochondrial membrane potentials and hence their activity. Additionally, there was less mitochondrial DNA damage noted in the treated group. This may also explain the demonstrated effect of preservation of hearing loss associated with aging, by the ability of PPC to specifically up regulate cochlear mitochondrial function.

How Probiotics Help You Absorb Crucial Nutrients

Robert Settineri, M.S., a nutriceutical research consultant and co-author of one of the human trials on Propax (a supplement which contains NT Factor®), reported to Health Sciences Institute in a March 2004 article that the probiotics in NT Factor® help improve the absorption of both the supplemental phospholipids in NT Factor®, as well as the other nutrients in the formula. He said “NT Factor supports the entire biodelivery system.” He continued, “the probiotics support the digestive tract and displace the pathogens which are competing for space. It prepares the digestive tract to absorb nutrients better, and phospholipids are absorbed in the gut.”

What Would You Do With MORE Energy? Are You Ready to Find Out?

Mitochondria Ignite™ with NT Factor® is fast gaining a reputation as the ultimate energy enhancing supplement, packed with all the power of the intact phospholipids in NT Factor® and the following combination of critical nutrients that work synergistically: calcium, phosphorus, magnesium, carnitine, creatine, and pantethine. If you are looking for reliable, long lasting and research proven energy enhancement and cellular support, look no further than Mitochondria Ignite™ with NT Factor®. Try this remarkable formula and discover what it can do for you.

References

1. Ellithorpe, Rita R., Settineri, Robert A., Nicolson, Garth L. Pilot Study: Reduction of Fatigue by Use of a Dietary Supplement Containing Glycophospholipids. JANA 2003; Vol. 6, #1.

2. Colodny L., Lynch K., Farber C., Papsih S., Phillips K., Sanchez M., Cooper K., Pickus O., Palmer D., Percy TB., Faroqui M., Block JB. Results of a study to evaluate the use of Propax [with NT Factor™] to reduce adverse effects of chemotherapy. JANA 2001; 3:17-25.

3. Agadjanyan M., Vasilevko V., Ghochikyan A., Berns P., Kesslak P., Settineri R., Nicolson G. Nutritional Supplement NT Factor™ Restores Mitochondrial Function and Reduces Moderately Severe Fatigue in Aged Subjects. J Chronic Fatigue Syndrome 2003; 11(4).

4. Seidman, Michael D. "Polyunsaturated phosphatidylcholine in NT Factor™ improves mitochondrial function, auditory sensitivity and may slow some of the aging processes." Anti-Aging Medical News. Winter 2001.

5. Seidman, Michael D., Khan, Mumtaz J., Tang, Wen Xue, Quirk, Wayne S. "Influence of lecithin [a polyunsaturated phosphatidylcholine] on mitochondrial DNA and age-related hearing loss." Otolaryngology-Head and Neck Surgery. September 2002.